CiproScrew™

Product Overview

As the world’s first antibiotic releasing bioabsorbable fixation device CiproScrew™ opens up new possibilities to prevent implant-related infections. CiproScrew™ releases a broad spectrum antimicrobial agent around itself inhibiting ciprofloxacin sensitive bacteria to colonize the surface of the screw, meanwhile being mechanically strong enough for fixation. Choose CiproScrew™ when your patient has an increased risk of infection.

The primary mode of action is fixation and the secondary mode of action is inhibition of ciprofloxacin sensitive organisms to colonize surface of the screw. Choose CiproScrew™ when your patient has an increased risk of infection.

CiproScrew™ is entirely compatible with AO-instrumentation.

CiproScrew™ is CE approved.


Not available in US market.

 

Benefits of using CiproScrew™

CiproScrew™ is indicated for fixation of bone fractures, osteotomies, arthrodeses, bone grafts and osteochondral fractures in the presence of appropriate immobilization when infection by ciprofloxacin sensitive organism is a potential risk.
Risk group patients are smokers, alcoholics, immunocompromised patients such as aged people and diabetics, and patients with open fractures.
The generally extremely challenging, long lasting and very expensive treatment of implant-related infection is needed in the cases where a risk of infection is realized.

 

 

 

 

  


 

Image: Bacterial culture (S. aureus) on a Petri-dish with a metallic screw on the left (A) and CiproScrew™ on the right (B) after 18 hours incubation at 35°C. The antibiotic effect on the S. aureus culture can easily be seen as a clear ring around the CiproScrew™.

 

    Image: Packaging, instrument and implant design enables aseptic and easy use in surgical procedure. 
     
   

 

 

Indication examples

Lower extremities

  • Ankle fractures
  • Talar fractures
  • Calcaneal fractures
  • Hallux valgus surgery (Proximal osteotomy or TMT-I arthrodesis)
  • Talocrural arthrodeses
  • Subtalar arthrodeses
  • Osteotomies
  • Tibial condylar fractures

Upper extremities

  • Distal clavicular fracture
  • Glenoid rim fractures
  • Proximal humeral neck fractures
  • Epiphyseolytic fractures in upper limb in children
  • Lateral humeral condyle fractures
  • Medial humeral condyle or epicondyle fractures
  • Olecranon fractrures
  • Distal radial fractures
  • Hand fractures
  • Scaphoideus

Material properties

Poly(L-lactide-co-glycolide) and Ciprofloxacin. Both raw materials are well known and generally used in orthopaedic applications. 

 

CiproScrew™ - The world’s first bioabsorbable bone fixation device with local drug release

 

 

Product range

CiproScrew™ is available in diameters 2.0, 2.7, 3.5, 4.5 and lengths up to 70 mm.

Brochure of CiproScrew™

Brochure CiproScrew_not valid in USA.pdf